Finally, no longer getting mouth ulcers multiple times per month!

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After decades of getting severe widespread mouth ulcers multiple times per month, often back to back, I am finally no longer getting them! While I do have extremely high levels of antibodies to hsv 1 and taking double dose of dakly Famvir for over 10 years, helped, I finally figured out my issue. It wasnt caused by foods, though eating high lysine and low arginne did help.

Nope, it seems for me NSAIDs cause mucusal injury which then causes my hsv - 1 (cold sore) virus to reactivate. Which for me, causes wide spread severe ulcers all over in my mouth and down my throat (and likely in my GI - but was never scoped to confirm).

I stopped taking NSAIDs (no aspirn, alieve, advil etc) almost 9 months ago. Instead of having 2 - 4 severe “outbreaks”per MONTH, Ive now had 3 in total! And I refuced my Famvir dose by 1/2!
The 3 outbreaks, I believe were triggered unfortunately by too high of a Tylenol
dose. Tylenol has a weak cox 1 and 2 inhibitor effect and it appears Im extremely sensitive. With experimentation, I can tolerate about 250 mg of tylenol per day. Over that amount and I start to get ulcerations, which if I take 1.5g of Famvir at the 1st sign, it typically stops it. Unfortunately, I have severe migraines and chronic pain, which means I have no effective otc pain medication options. However, not having almost continual mouth ulcers with flu like symptoms, has been a huge quality of life improvement.

If you havent considered nsaids, including tylenol, as a potential cause, it might be worth trying. I wish I had read the medical journal article I finally saw 9 months ago, decades ago. Thankfully, I finally figured it out!
Riley 25 December 19

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Finally, no longer getting mouth ulcers multiple times per month!

1 messages in this subject.